ADVOS multi

Targeted Multiple Organ Support

The ADVOS multi is an integrated multiple organ support device that enables fully individualised treatments with a focus on one or more leading organs, offering users the following benefits:

Click on the red dots to find out how the ADVOS multi works in the 3D model.

High user-friendliness of the information panel

  • User-friendly, intuitive information panel with dialysis-like menu guidance
  • Brightness adjustment of the screen possible, making it less disruptive to patients at night
  • Basic setting parameters are all selectable within one screen

Video-based assistance

  • Quick set-up and easy handling with video-based instruction
  • Step-by-step instructions with a high level of detail
  • Videos can be selected at any time, but are not compulsory for therapy

24 h service hotline for customer

  • 24 h service hotline for customers queries
    • DE 0800 43 72 92 74
    • AUT 0800 44 77 07
  • Service hotline answered by ADVITOS staff, not by external call centres
  • Free hotline 24/

Little user interaction

  • Little user interaction required during ongoing treatment
  • Tubing set does not need to be changed during treatment, even if anticoagulation is changed

Individually adjustable blood flow rates

  • Blood flow rates from 100 up to 500 ml/min to maximise toxin removal
  • High blood flow rates are particularly useful for small molecules such as H+
  • Low blood flow rates can be set for patients with circulatory instability
  • Blood flow adaptable to indications and access materials in hospitals

Systemic and regional anticoagulation possible

  • Systemic (e.g. heparin) and regional anticoagulation with citrate possible
  • Anticoagulation can be changed between citrate and systemic anticoagulation during treatment
  • Tubing set does not have to be changed when changing anticoagulation

Treatment duration of up to 24 hours

  • Intermittent or continuous treatment possible
  • Standard treatment duration of up to 24 hours
  • Single addition of human albumin (200 ml 20 %) in 24 hours

Flexible fluid management system

  • Flexible fluid management system that eliminates the need to connect to a reverse osmosis system at the point of treatment
  • Container with 85 l filling capacity eliminates the need for frequent bag changes - container only needs to be changed after up to 8 hours during treatment, depending on settings
  • External pump units for filling and emptying the container - eliminates the need to manually fill and empty the permeate and filtrate bags

Connection for citro disinfection

Technical Data

Height: 172 cm
Width: 66 cm
Depth: 84 cm (storage location item) 101 cm (work item)
Footprint: 62 cm x 63 cm
Empty weight: ADVOS multi 170 kg
Empty weight: Container 34 kg

Peripheral System

The optimum operating environment for the ADVOS multi includes the following additional equipment:

WDI Filling System

  • Power connection (230 volts)
  • Connection ring line osmosis water

The WDI system enables volume-controlled filling of the permeate bags with automatic shut-off after the filling quantity has been reached. For the installation of the WDI, a power connection and a connection to a ring line (osmosis water) are required.

As an alternative to the ring line (osmosis water), the company ADVITOS GmbH provides an osmosis system. Prerequisite for the installation of the system is a drinking water connection, electricity connection and a connection to the sewage network.

The installation of the system is carried out by ADVITOS GmbH.

FPU Pump-Out Unit

  • Power connection (230 volts)
  • Waste water connection

The FPU pump-off unit is used to empty the permeate and filtrate bags. A power connection and a connection to the waste water network are required for the installation of the pump-off unit.

The installation of the FPU pump-off unit is carried out by ADVITOS GmbH.

Treatment Set

The treatment set consists of consumables and disposable materials from the ADVOS multi. The set contains:

  • ADVOS multi filters and filter adapters as well as ADVOS multi dialysers.
  • Filtrate bag and permeate bag
  • ADVOS multi tubing set consisting of arterial and venous tubing set as well as the human albumin tubing
  • Three-way stopcock, which is the connecting piece between human albumin tubing and ADVOS multi

Alkaline Concentrate

The Alkaline Concentrate is part of the ADVOS haemodialysis system and is diluted with permeate to the target concentration. It is designed to raise the pH of the dialysate to allow water-soluble and protein-bound toxins to be dissolved and filtered off. 

It is important to note that the DiaProtect no longer has to be added separately, but is already integrated into the concentrates.

There are three different alkaline concentrates:

  • The alkaline concentrate BASE-BIC-20 Protect is the standard concentrate for use with the ADVOS multi.
  • The Alkaline Concentrate BASE-BIC-10 Protect is intended for lowering the bicarbonate content or for preventing an increased bicarbonate content in the blood.
  • The alkaline concentrate BASE-BIC-0 Protect is intended for the rapid reduction of the bicarbonate content in the blood.

Acidic concentrate

Acidic concentrate is part of the ADVOS haemodialysis system and is diluted with permeate to the target concentration. It is designed to lower the pH of the dialysate to allow water-soluble and protein-bound toxins to be dissolved and filtered off. 

There are 2 different acidic concentrates:

  • The acidic concentrate ACID-Ca-1 (with calcium) is intended for use with the ADVOS multi with systemic anticoagulation medications.
  • The acidic concentrate ACID-Ca-0 (without calcium) is used for regional citrate anticoagulation.

Permeate Supply

Ideally, the containers should be filled from a closed circular pipeline with the help of the WDI filling unit.

Container

ADVOS multi may only be operated with the corresponding containers and suitable permeate and filtrate bags.

ADVOS multi and the Benefits for Users

The ADVOS Procedure

Extracorporeal blood purification for simultaneous support of the primary excretory organs.

The ADVOS method is an innovative blood purification technology and represents a further development of conventional dialysis machines.

Instead of normal dialysate, dialysate enriched with human albumin is used, which enables the selective removal of certain toxins by specifically adjusting the pH value of the dialysis fluid. Within the machine, the dialysate is permanently processed and freed from toxins to achieve a consistently high detoxification performance.

Further information

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