{"id":7017,"date":"2023-07-18T12:16:57","date_gmt":"2023-07-18T10:16:57","guid":{"rendered":"http:\/\/neu.advitos.com\/?page_id=7017"},"modified":"2026-09-14T11:39:14","modified_gmt":"2026-09-14T09:39:14","slug":"milestones-history","status":"publish","type":"page","link":"https:\/\/advitos.com\/en\/advitos-gmbh\/about-us\/milestones-history\/","title":{"rendered":"Milestones \u2013 History"},"content":{"rendered":"\t\t
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The History of ADVITOS GmbH<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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ADVITOS GmbH started with a small team of researchers in Garching, Bavaria. Over the years, the team grew, successfully refined the ADVOS procedure and won numerous awards in the process.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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2004<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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ounding of Hepa Wash GmbH by Dr\u00a0Bernhard Kreymann.<\/p>

Hepa Wash GmbH takes 3rd place in the Munich business plan competition.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2005<\/span><\/span><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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A laboratory prototype of the dialysis device is built.
Research begins in laboratories at the Garching research campus.<\/p>

\u201cHepaClean\u201d funding programme \u2013 what was then known as the Hepa Wash procedure is established in cooperation with the Chair of Biochemistry and Medical Technology at the Technical University of Munich.<\/p>

The Bavarian Research Foundation subsidises ADVITOS GmbH (formerly Hepa Wash GmbH) to the amount of 300,000 euros.<\/p>

Hepa Wash takes 3rd place in the\u00a0Science4Life Business Plan competition.<\/a>\u00a0Founders, private investors and the Bayern Kapital venture capital company invest a total of 300,000 euros in seed capital.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Hepa Wash is awarded 2nd place at the New Venture Competition by Harvard Business School, USA.<\/p>

Start of in vitro testing of what was then known as the Hepa Wash procedure.<\/p><\/div><\/div><\/div><\/div><\/div><\/section><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The ethics board of the Rechts der Isar hospital grants approval to preclinical trials for acute liver failure.<\/p>

A prototype of the dialysis device is developed for the preclinical trial.<\/p>

Partners are found at the Rechts der Isar hospital in Munich to carry out the preclinical trials.<\/p>

Research funds to the amount of 120,000 euros are authorised by the Bavarian ministry of economics as part of the BayTOU funding programme.<\/p>

The effectiveness of what was then known as the Hepa Wash procedure is proved in vitro.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The company moves to the\u00a0Munich Technology Center (MTZ).<\/a><\/p>

Hepa Wash and the Medical Clinic II for Gastroenterology at the Rechts der Isar hospital receive 425,000 euros from the Bavarian Research Foundation for the preclinical trial \u201cPatal \u2013 pathogenesis and therapy of acute liver failure\u201d.<\/p>

In various different in vivo trial series, it is proved that what was then known as the Hepa Wash procedure lowers the mortality rate in cases of acute liver failure. It is possible to improve the most important organ functions.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2009<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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The Bavarian ministry of economics grants 770,000 euros to support development of the innovative liver dialysis procedure.<\/p>

Start of development and construction of the human prototype.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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2010<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Opening of the new laboratory and workshop space in the
Munich Technology Center (MTZ).<\/p>

The T\u00dcV S\u00fcd association certifies the human prototype in accordance with the Medical Device Directive MDD 93\/42 EEC, granting it technical clearance.<\/p>

The Federal Institute for Drugs and Medical Devices (BfArM) approves the first two clinical trials for approval of what was then known as the Hepa Wash procedure.<\/p>

The ethics board of the Rechts der Isar hospital in Munich approves clinical testing of what was then known as the Hepa Wash procedure.<\/p>

Hepa Wash reaches the final of the\u00a0Eurecan European Venture Contest<\/a>\u00a0in Barcelona.<\/p>

The German Federal Ministry for Economic Affairs grants 125,000 euros to fund development of in-house production of treatment fluids as part of the \u201cZIM\u201d central innovation programme for SMEs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The quality management system is certified by T\u00dcV S\u00fcd in accordance with ISO 13485.<\/p>

Hepa Wash GmbH is chosen as a \u201cselected site\u201d and award winner in the\u00a0\u201c365 locations in the Land of Ideas\u201d<\/a>\u00a0competition.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Expansion of in-house production of treatment concentrates.<\/p>

Expansion of the production area and the warehouse at the Munich Technology Center (MTZ).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The dialysis equipment developed (LK2001) and the treatment concentrates are certified in accordance with the Medical Device Directive (MDD) 93\/42 EEC Annex II.3, thus granting them market approval in Europe.<\/p>

The company has 26 full-time employees covering all the business-relevant fields.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Second place at the\u00a0Venture Lounge LifeScience & MedTech<\/a>\u00a0in Munich for an excellent company presentation and convincing business plan.<\/p>

Participation in the 2014 Innovation Days in Paris, ranked among the 15 finalists for the Innovation Prize.<\/p>

Membership of\u00a0Cluster Mechatronik & Automation e.V<\/a>.<\/p>

Participation in the HealthTech Summit in Lausanne, with a company presentation.<\/p>

Second place in the \u201cmost innovative product\u201d category at the 2014 senetics Innovation Award.<\/p>

Publication of an article on the subject of \u201cliver support therapies\u201d in the textbook \u201cFachpflege Nephrologie und Dialyse\u201d (specialist care in nephrology and dialysis).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Hepa Wash celebrates its 10-year anniversary.<\/p>

Selected exhibitor on the \u201cWalk of Future\u201d at the \u201cCouncil on the Future of Bavarian Industry: what Bavaria needs tomorrow\u201d event.<\/p>

Participation in and company presentation at the HealthTech Growth Academy in Aarhus, Denmark.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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The ADVOS multi therapy<\/a>\u00a0is used in 10 German university hospitals.<\/p>

The LK2001 multiple organ support device is renamed ADVOS multi.<\/p>

Staff expands to 35 employees.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Establishment of additional clinical centres.<\/p>

Expansion of sales and marketing in Germany.<\/p>

First international presence and approaches to clinics.<\/p>

Cooperation with\u00a0German Accelerator Life Sciences<\/a>\u00a0to prepare for expansion into the USA.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Personalaufstockung auf \u00fcber 55 Mitarbeiterinnen und Mitarbeiter.<\/p>

F\u00f6rderung durch das Bundesministerium f\u00fcr Bildung und Forschung.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Hepa Wash GmbH becomes ADVITOS GmbH.<\/p>

Support from\u00a0EIT Digital<\/a>, a committee of the European Union.<\/p>

Funding from the EU\u2019s \u201cHorizon 2020 Research and Innovation\u201d programme.<\/p>

Awarded the Seal of Excellence for first-class innovation ideas.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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Funding from the EIC Accelerator Project of the European Commission to deal with the coronavirus pandemic.<\/p>

Initial treatment of COVID-19 patients with promising results.<\/p>

First main prize at the Bavarian Innovation Prize<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Named the most innovative medical technology company in Germany in 2021.<\/p>

Named one of the 15 best social companies in Europe<\/p>

Finalist in the Social Innovation Tournament (SIT)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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ADVITOS welcomes new management \u2013 Dr\u00a0Claus Jessen appointed director.<\/p><\/div><\/div><\/div><\/div><\/div><\/section>

\u00a0<\/div><\/div><\/div><\/div><\/div><\/div><\/section>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Participation in the\u00a0Global Health Summit 2023<\/a>\u00a0in Geneva.<\/p>

First ADVOS users meeting with users from Germany and Austria.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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The CE-certified and globally patented ADVOS multi therapy has been certified in accordance with the highest EU standard for medical devices, the Medical Device Regulation (MDR), since 2024. This confirms the safety and quality of the certified products.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Milestone in extracorporeal blood treatment<\/strong>
ADVITOS presents the next generation of the ADVOS system at DIVI24: the ADVOS BK300<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The ADVOS BK300 was recognised with two Red Dot Design Awards in 2025, highlighting its outstanding product design.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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The ADVOS BK300 was honoured with one of the most prestigious accolades in the international design world, the iF Design Award Gold.<\/p>

ADVITOS GmbH became a cooperating member of the German Society of Internal Intensive Care and Emergency Medicine (DGIIN e.V.).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tMore Information<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

The History of ADVITOS GmbH ADVITOS GmbH started with a small team of researchers in Garching, Bavaria. Over the years, the team grew, successfully refined the ADVOS procedure and won numerous awards in the process. 2004 ounding of Hepa Wash GmbH by Dr\u00a0Bernhard Kreymann. Hepa Wash GmbH takes 3rd place in the Munich business plan […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":7085,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-7017","page","type-page","status-publish"],"yoast_head":"\n"ADVITOS history: from start-up to today "<\/title>\n<meta name=\"description\" content=\""ADVITOS history begins as a start-up of the TU in Munich. 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